Regulation of cell function by Rho GTPases

C DerMardirossian1, G M Bokoch

  • 1The Scripps Research Institute, Department of Immunology, La Jolla, California 92037, USA.

Summary

Rho GTPases are key regulators of cell functions. This review explores their biological activities, drug development potential using NADPH oxidase as an example, and strategies for targeting Rho GTPase pathways.

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