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Minocycline-induced staining of torus palatinus and alveolar bone
Lilibeth Ayangco1, Phillip J Sheridan
1Periodontics, Department of Dental Specialties, Mayo Clinic, Rochester, MN 55905, USA.
Background:
Minocycline hydrochloride, an analog of tetracycline, is widely used in the treatment of acne. Its use has been associated with discoloration of teeth, bone, and other tissues.
Methods:
A case is presented involving a patient with minocycline-induced staining of the torus palatinus and alveolar bone.
Results:
No treatment was rendered since the patient was not concerned with the appearance of the discoloration. The patient's dermatologist elected to change antibiotics.
Conclusions:
Patients on long-term minocycline therapy should be made aware of the possibility of pigmentation of bone and soft tissue that may be reversible with discontinuation of therapy; however, minocycline-induced staining of the permanent dentition may not be reversible.