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Updated: Sep 25, 2026
Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair
Published on: February 24, 2016
Effect of purified collagen on lipograft survival: experimental basis for periurethral lipoinjections
Paulo César Rodrigues Palma1, Benedicto Vidal, Cássio Luís Zanettini Riccetto
1Department of Urology, Faculty of Medical Sciences, State University of Campinas, UNICAMP, Campinas, São Paulo, Brazil.
Purpose:
To assess whether the use of collagens with lipografts improves graft survival.
Materials And Methods:
Thirty isogenic New Zealand rabbits were injected in the auricular area with either autologous fat alone or autologous fat associated with collagen. The animals were evaluated at 7, 30, and 90 days by histologic and morphometric methods together with measurements of the graft area and the number of adipocytes.
Results:
Addition of collagen to the lipoinjection reduced the local inflammatory reaction and improved the graft's survival; e.g., for stress urinary incontinence.
Conclusion:
These results suggest that it is possible to increase the survival rate of the lipografts and improve their clinical applicability.
