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Brugada-type electrocardiographic pattern induced by epidural bupivacaine
Nicole Phillips1, Mark Priestley, A Robert Denniss
1Department of Anesthesia, Westmead Hospital, Australia. nicolephillips@optusnet.com.au
Anesthesia and Analgesia
|June 24, 2003
Abstract
Implications:
In this case report, we describe the postoperative occurrence of electrocardiogram changes suggestive for the Brugada syndrome in a patient receiving a continuous epidural bupivacaine infusion. After withdrawal of bupivacaine, the electrocardiogram changes were reversible. The patient's history was unremarkable except for an incomplete right bundle branch block. We conclude that local anesthetics, particularly bupivacaine, have the potential to induce serious arrhythmias in patients with Brugada syndrome.