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Related Experiment Videos

Weaning preterm infants: a randomised controlled trial.

L D Marriott1, K D Foote, J A Bishop

  • 1School of Biomedical and Life Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK. ldm@mrc.soton.ac.uk

Archives of Disease in Childhood. Fetal and Neonatal Edition
|June 24, 2003
PubMed
Summary

A new weaning strategy for preterm infants improved length growth and iron status. This approach, focusing on early introduction of nutrient-dense foods, offers significant benefits for infant development.

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Area of Science:

  • Neonatal nutrition
  • Pediatric growth and development
  • Infant iron status

Background:

  • Preterm infants often face challenges with growth and nutrient deficiencies post-discharge.
  • Current feeding practices may not fully optimize nutritional intake for preterm infants.
  • Early introduction of solids is a critical period for nutrient acquisition.

Purpose of the Study:

  • To evaluate a specialized preterm infant weaning strategy.
  • To compare this strategy against current best practices in infant feeding.
  • To assess the impact on growth parameters and iron status.

Main Methods:

  • A blinded, controlled study involving 68 preterm infants from hospital discharge to 1 year corrected age.
  • Infants were randomized into a preterm weaning strategy group or a control group.

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  • Growth (weight, length, head circumference) and nutrient intake were monitored; hemoglobin, serum iron, and ferritin levels were assayed.

    • Main Results:

    • The preterm weaning strategy group showed significant improvements in length growth velocity and standard deviation length scores.
    • Increased intake of energy, protein, carbohydrate, and iron was observed at 6 and 12 months corrected age.
    • Hemoglobin and serum iron levels were significantly higher at 6 months corrected age in the intervention group.

    Conclusions:

    • The specialized preterm weaning strategy positively impacted dietary intake, leading to enhanced linear growth and iron status.
    • This feeding approach demonstrates significant benefits for preterm infants after hospital discharge.
    • The findings support the adoption of this strategy in feeding guidelines for preterm infants.