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Updated: Jul 11, 2026

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model
Published on: September 29, 2011
[Analysis of nonlinear dynamics of aging (experimental study)]
1N.M. Emanuel Institute of Biochemical Physics of the Russian Academy of Sciences, 4, Kosygina Str., Moscow, 119991. soloviova@mtu-net.ru
Abstract:
The research is devoted to the analysis of individual dependencies of weight of a body, rectal temperature and functional motor asymmetry of behavior of mice female CBA from age received in longitudinal research. Both individual, and the average age dependencies of the above named parameters have an extreme (nonlinear) kind. It is revealed, that by the age of achievement of the maximal weight (Tm) and greatest asymmetry of behavior (Tn) are connected with each other (r = 0.6, p < 0.001). The difference (Tm-Tn) is linearly connected to life expectancy (r = 0.62, p < 0.001), that is this parameter can be used for the forecast of individual life expectancy.
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