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Updated: Aug 17, 2026

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
Published on: October 31, 2010
Opportunities and options for treatment research in resource-constrained settings
1University of California San Francisco and San Francisco Veterans Affairs Medical Center, San Francisco, CA 94121, USA. Paul.Volberding@med.va.gov
Abstract:
HIV clinical research faces limitations even in research-rich settings. Even though important questions remain unanswered, clinical trials will probably never be conducted that address, prospectively, when treatment is optimally indicated, for example. In resource-constrained settings, large, prospective clinical trials are also unlikely. On the other hand, ones with a more observational design or that compare cohort experiences may well be feasible and able to provide information important in those settings, as well as in regions with abundant financial resources.
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