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Acute infectious diarrhea in children
Sead Ahmetagic1, Ekrem Jusufovic, Jasminka Petrovic
1Infectious Diseases Clinic, University Clinical Center Tuzla.
Insights
Acute infectious diarrhea is a major global health issue, particularly for children. Rotavirus was identified as the most frequent pathogen causing infectious diarrhea in children in Tuzla, Bosnia and Herzegovina.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Acute infectious diarrhea poses a significant global health challenge, especially for infants and children, contributing to high morbidity and mortality rates.
- Understanding the etiology and characteristics of infectious diarrhea in children is crucial for effective public health interventions.
Purpose of the Study:
- To investigate the etiology of acute infectious diarrhea in children.
- To analyze the biochemical, epidemiological, and clinical characteristics of children experiencing fatal infectious diarrhea.
Main Methods:
- A study was conducted on 201 children aged 6 months to 14 years admitted to the Infectious Diseases Clinic in Tuzla between December 1999 and December 2000.
- Stool samples were analyzed to identify enteropathogens, with a focus on viruses, bacteria, fungi, and parasites.
Main Results:
- Enteropathogens were detected in 51.3% of the children. Viruses were the most common (25.4%), followed by bacteria (21.9%).
- Rotavirus was the most frequently identified pathogen (23.9%), followed by Salmonella species (10%) and EPEC (4.9%).
- Highest morbidity was observed in children under 2 years old (70.5%) and in the rural community (68.4%). Rotavirus detection peaked in winter and autumn and decreased with age. Blood in stool was most common in shigellosis cases (22.2%).
Conclusions:
- The high incidence of acute infectious diarrhea in infants and children represents a significant socio-economic and medical burden in the Tuzla region.
- Rotavirus stands out as the predominant pathogen responsible for infectious diarrhea among children in this study population.
Introduction:
Acute infectious diarrhea is a global health problem especially in infants and children, and is a leading cause of morbidity and mortality. The ethiology of acute infectious diarrhea and also biochemical, epidemiological and clinical characteristics of children dying with infectious diarrhea are investigated in this study.
Methods:
201 children, aged from 6 months to 14 years, with acute infectious diarrhea admitted to the Infectious Diseases Clinic in Tuzla in the period from 21st December 1999 to 21st December 2000 were included in the study.
Results:
Enteropathogens were identified in stool samples in 103 (51.3%) of 201 examined children. Viruses were identified in 51 (25.4%) cases, bacteria in 44 (21.9%), fungi in 3 (1.5%), and parasites in 2 (1%). Rotavirus, a frequent pathogen, was detected in 48 cases (23.9%), followed by Salmonella species in 20 (10%), EPEC in 10 (4.9%), and Shigella species in 9 (4.5%) cases. In this study the authors noticed that the highest morbidity was recorded in children in the first 2 years of life (70.5%), and among rural community (68.4%). The detection of rotavirus decreased with increasing age of cases and peaked in winter and autumn. Blood in stool was most common in children with shigellosis (22.2%).
Conclusions:
High percentage of infants and children dying with acute infectious diarrhea presents a serious socio-economic and medical problem in Tuzla region of Bosnia and Herzegovina. Rotavirus is the single most common pathogen in children with infectious diarrhea.
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