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Synthesis and biological activity of bactobolin glucosides
Hayamitsu Adachi1, Yoshio Nishimura
1Institute of Microbial Chemistry, 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021, Japan.
Natural Product Research
|June 26, 2003
Abstract:
Bactobolin glucosides, 5-O-(alpha-D-glucopyranosyl)-, 5-O-(beta-D-glucopyranosyl)- and 6-O-(beta-D-glucopyranosyl)-bactobolin were prepared by glycosidation of bactobolin (1) with the glucopyranosyl trichloroacetoimidate. These compounds were evaluated antimicrobial activity and cytotoxicity.