Related Experiment Video
Updated: Jun 25, 2026

11:22
Using Three-color Single-molecule FRET to Study the Correlation of Protein Interactions
Published on: January 30, 2018
Synthesis and characterization of a macrocyclic near-infrared optical scaffold
Yunpeng Ye1, Wen Ping Li, Carolyn J Anderson
1Department of Radiology, Washington University, St. Louis, Missouri 63110, USA.
Journal of the American Chemical Society
|June 26, 2003
Abstract:
Macrocyclization of a bioactive peptide with a bifunctional near-infrared fluorescent optical probe gives a compound that retained the receptor binding affinity of the peptide and the photophysical properties of the optical probe. The robust nature of the new compound provides a structural framework for optimizing the activity of bioactive molecules and for monitoring chemical or biological processes in vivo and in vitro by near-infrared optical methods.

