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Updated: Sep 23, 2026

The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
Published on: April 10, 2015
A trinuclear heterobimetallic Ru(II)/Pt(II) complex as a chemodosimeter selective for sulfhydryl-containing amino
Cheuk-Fai Chow1, Brenda K W Chiu, Michael H W Lam
1Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR, China.
Abstract:
A trinuclear heterobimetallic Ru(II)/Pt(II) complex, cis-{Ru(phen)2[CN-Pt(DMSO)Cl2]2} (phen = 1,10-phenanthroline), is able to function as a "switch-on" luminescent chemodosimeter for sulfhydryl-containing amino acids and peptides via specific binding of the amino acids/peptides with the Pt(II) centers and the subsequent cleavage of the Ru(II)-Pt(II) cyano-bridge.
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