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Plummer-Vinson syndrome.

K Atmatzidis¹, B Papaziogas, T Pavlidis

¹2nd Surgical Clinic of the Aristotle University of Thessaloniki, Greece.

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus

|June 26, 2003

Summary

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Plummer-Vinson syndrome, a condition causing difficulty swallowing and anemia, was effectively treated in two middle-aged women using iron supplementation. This treatment resolved symptoms, demonstrating a successful management strategy for this rare disorder.

Area of Science:

Medicine
Gastroenterology
Hematology

Background:

Plummer-Vinson syndrome is a rare disorder characterized by the triad of dysphagia, iron deficiency anemia, and esophageal webs.
Early diagnosis and treatment are crucial for managing symptoms and preventing long-term complications.

Observation:

Two middle-aged women presented with classic symptoms of Plummer-Vinson syndrome, including dysphagia, anemia, sideropenia, glossitis, and cheilitis.
Radiological examinations confirmed the presence of esophageal webs in both patients.

Findings:

Treatment with iron supplementation led to the complete resolution of dysphagia and anemia in both cases.
Patients experienced significant symptom improvement, with no recurrence of dysphagia at 5 and 8-year follow-ups.

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Implications:

Iron supplementation is a highly effective treatment for Plummer-Vinson syndrome.
Prompt diagnosis and management can restore normal swallowing function and improve quality of life.
This case report highlights the importance of recognizing and treating iron deficiency in patients with dysphagia.