Related Experiment Video
Updated: Sep 23, 2026
07:25
In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis
Published on: May 4, 2017
Treatment of resistant pemphigus vulgaris with an anti-CD20 monoclonal antibody (Rituximab)
H L Cooper1, E Healy, J M Theaker
1Dermatopharmacology Unit, University of Southampton, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK.
Clinical and Experimental Dermatology
|June 26, 2003
Abstract:
We describe a 54-year-old man with resistant pemphigus vulgaris. Standard therapies had afforded inadequate control and have been associated with considerable side-effects. The anti-CD20 monoclonal antibody, Rituximab (MabThera, Roche), was trialled with significant benefit. We discuss its potential mechanism of action.
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