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Updated: Sep 23, 2026

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Published on: April 7, 2015
Evidence of an association between Chlamydia pneumoniae and cerebrovascular accidents
1Neurology Service, Veterans Affairs Medical Center, Philadelphia, PA 19104, USA. gabriel.bucurescu@med.va.gov
Abstract:
The authors report results of a retrospective pilot study showing a strong association between patients with stroke/TIA and the presence of circulating IgG and IgA antibodies to Chlamydia pneumoniae. These results support the hypothesis that chronic active or persistent infection may play a role in the mechanism of thrombosis. The risk for stroke associated with Chlamydial circulating antibodies appeared to be independent of other risk factors such as diabetes and hypercholesterolemia.
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