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Related Experiment Videos

ChipInfo: Software for extracting gene annotation and gene ontology information for microarray analysis.

Sheng Zhong1, Cheng Li, Wing Hung Wong

  • 1Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA.

Nucleic Acids Research
|June 26, 2003
PubMed
Summary

ChipInfo simplifies obtaining and organizing Affymetrix microarray annotation data from online databases. This tool aids researchers by providing easily accessible, updated information for probe sets and Gene Ontology terms.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Assembling comprehensive annotation information for Affymetrix microarrays is complex and time-consuming.
  • Existing methods are prone to errors and present challenges for researchers.

Purpose of the Study:

  • To develop a software tool, ChipInfo, for efficient retrieval and organization of microarray annotation data.
  • To provide users with easily interpretable tabular outputs of probe set and Gene Ontology information.

Main Methods:

  • ChipInfo retrieves annotation data from online databases like NetAffx and Gene Ontology.
  • It organizes this information into user-friendly tabular formats.
  • The software also computes summary statistics for probe sets and Gene Ontology terms.

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Main Results:

  • ChipInfo successfully consolidates complex annotation data into accessible formats.
  • It functions as companion software, enabling updates for dChip and GoSurfer.
  • Users can efficiently access and analyze probe set and Gene Ontology data.

Conclusions:

  • ChipInfo offers a valuable solution for managing Affymetrix microarray annotation data.
  • The tool streamlines data retrieval and organization, saving researchers time and reducing errors.
  • ChipInfo enhances the usability of microarray data analysis in bioinformatics research.