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Updated: Sep 23, 2026

Biological Preparation and Mechanical Technique for Determining Viscoelastic Properties of Zonular Fibers
Published on: December 16, 2021
[Duo-Bonharen--a new viscoelastic preparation. Experimental study]
A al-Farzai1, J Novák, F Hubálek
1Ocní klinika, Fakultní Nemocnice a Lékarská fakulta v Hradci Králové Univerzity Karlovy v Praze.
Abstract:
The paper discusses preclinical tests of a new viscoelastic preparation for ophthalmosurgery. Experiments revealed that preparation Duo-Bonharen which contains hyaluronic acid prepared by bacterial fermentation is suited for clinical tests. After a 24-hour interval following administration into the anterior chamber it does not raise intraocular pressure. In experiments it has no side-effects on the eye. The dispersed form in a higher concentration (5%) adheres very well to ocular tissues and protects them adequately during surgery. The cohesive form in an optimal concentration (1.5%) can be rapidly removed from inside the eye. The properties of Duo-Bonharen in experiments are comparable with similar viscomaterials which are used. The new viscoelastic material Duo-Bonharen appears suitable for clinical tests in particular for cataract surgery.
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