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Related Experiment Videos

Calcium phosphate bone cements: a comprehensive review.

Denton D Weiss1, Matthew A Sachs, Charles R Woodard

  • 1Eastern Virginia Medical School, Department of Otolaryngology, Norfolk, Virginia 23507, USA. weissdd@evmsmail.evms.edu

Journal of Long-Term Effects of Medical Implants
|June 27, 2003
PubMed
Summary

Calcium phosphate cements (CPCs) accelerate bone healing in surgeries. Differences in their chemical makeup affect performance, informing clinicians and researchers about various CPC options.

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Area of Science:

  • Biomaterials Science
  • Orthopedic Surgery
  • Regenerative Medicine

Background:

  • Calcium phosphate cements (CPCs) are vital bone substitutes in craniofacial and maxillofacial surgery.
  • CPCs significantly accelerate healing of bone fractures and defects.
  • Despite a common function, subtle chemical variations influence CPC behavior in vivo.

Purpose of the Study:

  • To delineate the differences among major calcium phosphate cements (CPCs).
  • To provide clinicians and researchers with expanded knowledge on CPC variations.
  • To reference specific clinical trials where applicable.

Main Methods:

  • Comparative analysis of major calcium phosphate cements (CPCs).
  • Literature review focusing on in vivo performance and chemical composition.

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  • Inclusion of data from relevant clinical trials.

    • Main Results:

    • Identified significant differences in the in vivo characteristics of various CPCs.
    • Highlighted the impact of minor chemical composition variations on CPC performance.
    • Compiled data from clinical studies to support findings.

    Conclusions:

    • Understanding CPC chemical differences is crucial for optimizing bone healing outcomes.
    • This knowledge enhances the informed selection and application of CPCs in clinical practice.
    • Further research into CPC variations will refine their use as bone substitutes.