Related Experiment Video
Updated: Aug 16, 2026

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
Published on: March 20, 2017
Medical management of obesity
1Medical Department, Hospital Barmherzige Brüder, Romanstrasse 93, 80639, Munich, Germany. Prof.Wechsler@barmherzige-muenchen.de
Obesity management requires an interdisciplinary approach. Effective weight loss involves very low-calorie diets, followed by fat-reduced, carbohydrate-rich diets, with medication and surgery as adjuncts for specific cases.
Area of Science:
- Obesity Medicine
- Metabolic Disease Research
Background:
- Obesity is a growing global health concern, defined as a chronic disease by the World Health Organization.
- It is linked to increased rates of illness and mortality.
- Current treatment success rates are often suboptimal.
Purpose of the Study:
- To outline an interdisciplinary and multimodal approach for treating overweight and obesity.
- To identify effective dietary strategies for significant body fat reduction.
- To clarify the role of pharmacotherapy and surgical interventions in obesity management.
Main Methods:
- Review of current obesity treatment modalities.
- Emphasis on dietary interventions, including very low-calorie diets (VLCDs) and subsequent macronutrient adjustments.
- Integration of pharmacotherapy and surgical options within comprehensive weight management programs.
Main Results:
- Very low-calorie diets followed by fat-reduced, carbohydrate-rich diets yield the best results for body weight and fat loss.
- Weight-loss medications are most effective when integrated into a program of diet and physical activity.
- Surgical intervention is reserved for individuals unresponsive to conservative treatments.
Conclusions:
- Structured, guideline-oriented, and quality-controlled programs are essential for effective obesity treatment.
- A multidisciplinary strategy is crucial for long-term patient success.
Related Concept Videos
Obesity
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
Drug Dosing: Obese Patients
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Atherosclerosis III: Management

