Development of hand function among children with cerebral palsy: growth curve analysis for ages 16 to 70 months

Steven E Hanna1, Mary C Law, Peter L Rosenbaum

  • 1Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada. hannas@mcmaster.ca

Insights

This study tracked young children with cerebral palsy (CP) and upper-extremity involvement. Hand function develops differently than overall upper-extremity skills, with declines more common in older children.

Area of Science:

  • Pediatric Rehabilitation
  • Neurodevelopmental Disorders
  • Motor Function Assessment

Background:

  • Cerebral palsy (CP) significantly impacts motor development in children.
  • Understanding the trajectory of hand and upper-extremity function is crucial for early intervention.
  • Upper-extremity involvement is a common characteristic of CP, affecting daily activities.

Purpose of the Study:

  • To document the longitudinal development of hand and upper-extremity function in young children with CP.
  • To identify factors influencing developmental trajectories, including CP distribution and impairment severity.
  • To analyze interindividual variations in functional development over time.

Main Methods:

  • Longitudinal study design with assessments over 10 months.
  • Inclusion of 51 children (29 males, 22 females) aged 16-60 months at baseline.
  • Application of linear mixed effects modeling to analyze developmental curves and individual differences.

Main Results:

  • Hand function and upper-extremity skills show distinct developmental patterns in children with CP.
  • Declines in upper-extremity skills were more prevalent and pronounced in older children within the cohort.
  • CP distribution and impairment severity significantly predicted developmental outcomes, with considerable individual variation observed.

Conclusions:

  • The development of hand function diverges from general upper-extremity skills in pediatric CP.
  • Clinical interventions should consider the specific patterns of upper-extremity skill development and individual variability.
  • Severity and body-site distribution of CP are key factors influencing functional outcomes in young children.