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Two unusual acetogenins from the roots of Annona salzmanii
Emerson F Queiroz1, François Roblot, Olivier Laprévote
1Laboratoire de Pharmacognosie, CNRS UPRES-A 8076 (BIOCIS), Faculté de Pharmacie, 92296 Châtenay-Malabry, France. Emerson.ferreiraqueiroz@ipp.unil.ch
Journal of Natural Products
|June 28, 2003
Abstract:
Two new acetogenins, parisin (1) and salzmanolin (2), were isolated from a MeOH extract of the roots of Annona salzmanii. The structures of 1 and 2 were elucidated by spectroscopic methods including LSI-MS/MS, on both the natural compounds and their acetonide derivatives (1a and 2a). Compounds 1 and 2 showed significant activity against the KB and Vero cell lines.