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Updated: Aug 17, 2026

Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature
Published on: October 14, 2022
An effective extraction technique for the treatment of closed macrocomedones
Tamer Irfan Kaya1, Umit Tursen, Aysin Kokturk
1Department of Dermatology, Mersin University, Mersin, Turkey. tikaya@mersin.edu.tr
Background:
Closed macrocomedones are unsightly lesions that may be resistant to medical treatments and comedone extractors. Light cautery has been used to treat macrocomedones, which are 1 to 3 mm in size; however, its success in larger and chronic lesions is limited.
Objective:
To introduce an alternative treatment technique for this neglected problem.
Methods:
We treated these lesions by using cautery and standard dissecting forceps. After puncturing the macrocomedones in the center using the sharp-tipped cautery point, we grasped the base of the comedone using standard dissecting forceps and squeezed and pulled out the contents.
Results:
Twelve patients were treated with this technique, all of whom tolerated the procedure well and judged the cosmetics results as very good.
Conclusion:
We recommend this procedure for patients who have closed macrocomedones larger than 3 mm in size, although it is an effective treatment for macrocomedones of any size.

