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Fatal septic shock caused by Corynebacterium D2.
Vincent Audard1, Maité Garrouste-Orgeas, Benoit Misset
1Medical-Surgical ICU, Saint Joseph Hospital, 185 rue Raymond Losserand, 75014, Paris, France.
Intensive Care Medicine
|June 28, 2003
Summary
Septic shock from Corynebacterium D2 is rare but serious. This case highlights the potential for severe infection even in immunocompetent individuals, emphasizing the need for timely diagnosis and treatment.
Area of Science:
- Infectious Diseases
- Critical Care Medicine
- Nephrology
Background:
- Septic shock is a major cause of death in critically ill patients.
- Early diagnosis and pathogen identification are crucial for effective antibiotic therapy.
Observation:
- A case of septic shock caused by Corynebacterium D2 is presented.
- Corynebacterium D2 is typically associated with encrusted cystitis and pyelitis in kidney transplants.
- This microorganism can also affect native kidneys, leading to severe urinary tract inflammation.
Findings:
- Diagnosis involved identifying risk factors, positive urine cultures, and CT scan results.
- Despite treatment, the patient experienced persistent encrusted pyelitis and succumbed to septic shock.
- Corynebacterium D2 can cause severe septic shock, even in immunocompetent patients.
Implications:
- This case underscores the potential severity of Corynebacterium D2 infections beyond typical urinary tract presentations.
- Highlights the importance of considering unusual pathogens in severe sepsis.
- Emphasizes the need for prompt and accurate diagnosis in managing septic shock.