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[Changes of homeostasis and immunity in the acute period of ischemic stroke]

E M Burtsev, V B Grinshteĭn, S B Nazarov

    Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
    |July 2, 2003
    PubMed

    We studied homeostasis, immunity and rheological blood properties in the acute period of ischemic stroke. As intravascular blood coagulation and depression of fibrinolysis happen the amount of "rough" red blood cells increased as well as their aggregates enlarged in size. These changes haven't been seen in patients with lacunar stroke and transient ischemic attacks. Deep depression of T-cell immunity in stroke and inhibition of total fibrinolysis were observed. The most significant depression of cells immunity was found in patients with poor outcome. We recommend to evaluate T-cell immunity in stroke patients and proceed immunocorrection of necessity.

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