Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Comments on oocyte cryopreservation.

Fernando Marina1, Simón Marina

  • 1Instituto de Reproducción CEFER, Barcelona, Spain. info@institutocefer.com

Reproductive Biomedicine Online
|July 2, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Errors at mitotic segregation early in oogenesis and at first meiotic division in oocytes from donor females: comparative genomic hybridization analyses in metaphase II oocytes and their first polar body.

Fertility and sterility·2009
Same journal

Time to reconsider who the freeze-all approach benefits: a matched cohort analysis of over 9000 embryo transfers.

Reproductive biomedicine online·2026
Same journal

Structured counselling and its association with IVF cycle cancellations and patient adherence.

Reproductive biomedicine online·2026
Same journal

hsa-miR-375-3p in embryo culture medium exosomes as a preimplantation non-invasive biomarker for predicting live birth after IVF.

Reproductive biomedicine online·2026
Same journal

Promoting family-building strategies among key stakeholders: the International Federation of Fertility Societies More Joy™ campaign.

Reproductive biomedicine online·2026
Same journal

Ovarian reserve markers in World Health Organization type 1 anovulatory disorders: a systematic review and meta-analysis.

Reproductive biomedicine online·2026
Same journal

Effect of embryo culture medium pH on live birth rate after IVF/ICSI: a double-blind, multicentre, randomized trial.

Reproductive biomedicine online·2026
See all related articles

This study refutes claims that freezing human oocytes causes harm. Evidence shows oocyte cryopreservation offers comparable success rates to fresh oocytes and embryos in assisted reproduction.

Area of Science:

  • Reproductive Medicine
  • Genetics and heredity

Background:

  • Public concerns exist regarding potential harm to future generations from human oocyte cryopreservation.
  • The efficacy of oocyte freezing is debated in the context of assisted reproductive technologies.

Purpose of the Study:

  • To refute claims of irreparable harm caused by human oocyte freezing.
  • To present data on the efficacy of oocyte cryopreservation compared to fresh oocytes and embryos.
  • To examine the legal landscape of oocyte freezing in Spain.

Main Methods:

  • Literature review of studies comparing pregnancy and birth rates for fresh oocytes, frozen oocytes, and frozen embryos.
  • Analysis of data on the number of oocytes required per pregnancy.
  • Description of the legal framework and institutional experiences with oocyte freezing in Spain.

Related Experiment Videos

Main Results:

  • Data suggests that oocyte freezing requires a variable number of oocytes per pregnancy, with some studies indicating efficacy comparable to fresh oocytes and embryos.
  • Pregnancy rates per cycle using frozen oocytes (17.2%) were similar to frozen embryos (18.7%).
  • Reported birth rates indicate fresh oocytes (57.9%), frozen embryos (52.9%), and frozen oocytes (45.8%) yield successful outcomes.

Conclusions:

  • The assertion that human oocyte freezing causes irreparable harm is not supported by current scientific evidence.
  • Oocyte cryopreservation presents a viable option in assisted reproduction with outcomes comparable to established methods.
  • Legal uncertainties surrounding oocyte freezing highlight the need for clear regulatory guidance.