Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Deriving heart period variability from blood pressure waveforms.

Paula S McKinley1, Peter A Shapiro, Emilia Bagiella

  • 1Behavioral Medicine Program, Dept. of Psychiatry, College of Physicians and Surgeons, Columbia Univ., 622 W. 168th St., PH Bldg. Suite 11-460 (stem New York, NY 10032, USA. pm491@columbia.edu

Journal of Applied Physiology (Bethesda, Md. : 1985)
|July 2, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lessons Learned from the Feasibility Phase of the REvascularization CHoices Among Under-Represented Groups Evaluation (RECHARGE) Trial Program.

American heart journal·2026
Same author

Nintedanib in Post-COVID Interstitial Lung Disease: a double-blind, randomized, placebo-controlled Clinical Trial.

Annals of the American Thoracic Society·2026
Same author

Association of tricuspid regurgitation with clinical events and quality of life after surgery for severe ischemic mitral regurgitation.

JTCVS structural and endovascular·2026
Same author

Blood mitochondrial heteroplasmic variants and cognitive performance in late midlife: REGARDS study.

BMC neurology·2026
Same author

Mitral Valve Repair for Degenerative MR With Moderate or Less Tricuspid Regurgitation: 2-Year Outcomes From a Multicenter Echocardiographic Core Laboratory-Adjudicated Cohort.

Journal of the American College of Cardiology·2026
Same author

Topical vancomycin for surgical site infection prophylaxis in craniotomies and noninstrumented spinal procedures: a randomized controlled trial.

Journal of neurosurgery·2025

Blood pressure (BP) waveforms can reliably estimate heart period variability (HPV) in healthy adults. This finding validates using BP monitoring for assessing cardiovascular autonomic function, complementing traditional electrocardiogram (ECG) methods.

Area of Science:

  • Cardiovascular Physiology
  • Autonomic Nervous System Function
  • Biomedical Signal Processing

Background:

  • International standards exist for calculating heart period variability (HPV) using electrocardiogram (ECG) R-wave intervals.
  • Estimating HPV from blood pressure (BP) waveforms is potentially useful but lacks established validity.
  • Assessing the reliability of BP-derived HPV is crucial for expanding non-invasive cardiovascular monitoring.

Purpose of the Study:

  • To evaluate the reliability of HPV indexes derived from BP waveforms compared to ECG-derived HPV.
  • To determine if BP waveforms can serve as a valid alternative for HPV assessment.
  • To investigate the consistency of HPV measures across different physiological stress conditions.

Main Methods:

  • Utilized continuous ECG and BP recordings from 234 healthy adults across four studies.

Related Experiment Videos

  • Data were sampled at 500 Hz and analyzed using standardized scoring methods.
  • Calculated heart rate and time- and frequency-domain HPV indexes from both ECG and BP waveforms.

    • Main Results:

    • Demonstrated very high overall reliability between BP- and ECG-derived heart rate and HPV indexes.
    • Identified high-frequency HPV indexes as being somewhat less reliably computed between the two methods.
    • Confirmed strong concordance between the two measurement techniques in healthy adults.

    Conclusions:

    • BP waveforms can produce reliable indexes of HPV in healthy adults when appropriate methods are employed.
    • BP-derived HPV offers a potentially valuable and accessible method for assessing autonomic function.
    • This validates the use of BP monitoring for cardiovascular variability assessment, supporting its clinical and research applications.