Abdominal aortic aneurysms and concomitant coronary artery disease. Is routine dipyridamole thallium scintigraphy

R B Galland1

  • 1Department of Surgery, Royal Berkshire Hospital, Reading, UK. Robert.Galland@rbbh-tr.nhs.uk

Insights

Identifying coronary artery disease in peripheral vascular disease patients undergoing abdominal aortic aneurysm repair is crucial. Routine cardiac investigations like dipyridamole thallium scanning are not justified due to lack of proven benefit.

Area of Science:

  • Cardiology
  • Vascular Surgery
  • Diagnostic Imaging

Background:

  • High prevalence of coronary artery disease (CAD) in peripheral vascular disease (PVD) patients.
  • Cardiac complications are the leading cause of perioperative death after abdominal aortic aneurysm (AAA) repair.
  • Risk stratification for perioperative cardiac events is possible through clinical assessment and investigations.

Purpose of the Study:

  • To evaluate the utility of dipyridamole thallium scanning (DTS) in identifying myocardial ischemia in PVD patients undergoing AAA repair.
  • To determine if identifying and correcting CAD improves perioperative mortality or long-term survival in these patients.

Main Methods:

  • Review of dipyridamole thallium scanning (DTS) findings in patients with PVD.
  • Analysis of evidence regarding the impact of CAD identification and correction on perioperative outcomes.
  • Consideration of risk stratification methods including clinical evaluation, stress testing, and ejection fraction measurement.

Main Results:

  • DTS reveals normal scans, reversible defects, or fixed defects in approximately one-third of PVD patients.
  • Delayed scans indicate some "fixed" defects are reversible, suggesting myocardial ischemia.
  • No evidence supports improved operative mortality or long-term survival from identifying and treating CAD in asymptomatic patients.

Conclusions:

  • Routine use of DTS or other cardiac investigations for all PVD patients undergoing AAA repair is not justified.
  • While high-risk patients may warrant investigation, optimizing medical treatment may be preferable to revascularization or delaying aneurysm repair.
  • The benefit of identifying and correcting CAD in asymptomatic patients undergoing AAA repair remains unproven.

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