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An open pilot study using tacrolimus ointment in the treatment of seborrheic dermatitis
Azin Meshkinpour1, Joannie Sun, Gerald Weinstein
1University of California, Irvine, USA.
Journal of the American Academy of Dermatology
|July 2, 2003
Abstract:
Seborrheic dermatitis is generally treated with topical steroids, antifungals, or both. This pilot study was undertaken to examine the possibility of tacrolimus as a useful therapy for seborrheic dermatitis. In a single-center, open-label study, 18 consecutive patients with seborrheic dermatitis were treated with 0.1% tacrolimus for a total of 28 days or until complete clearance occurred, if sooner. Of the patients, 11 (61%) showed 100% clearance of their seborrheic dermatitis; the remaining 7 patients showed 70% to 99% clearance. The most common side effects were mild local burning and irritation.