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Updated: Jul 30, 2026

Quantitative Autonomic Testing
Published on: July 19, 2011
Drug-induced sweat gland necrosis in a non-comatose patient: a case presentation
C Ferreli1, V I Sulica, N Aste
1Department of Dermatology University of Cagliari, Cagliari, Italy. ferreli@unica.it
Background:
Coma-induced bullae and sweat gland necrosis is a rare clinicopathological entity often associated with drug-induced coma.
Subject:
We report a case with clinical and histopathologic findings characteristic of blisters and sweat gland necrosis occurring in a non-comatose patient.
Conclusions:
Skin blisters with underlying sweat gland necrosis is an entity previously reported to occur in comatose patients, our findings open new questions about the role of the drugs in the pathogenesis of those conditions.
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