Related Experiment Videos

Xanthogranulomatous pyelonephritis with multiple cutaneous fistulae

R G Gerridzen1, W Morris

  • 1University of Ottawa and Ottawa Civic Hospital, Ottawa, Ontario.

The Canadian Journal of Urology
|January 1, 1994
PubMed

Insights

Xanthogranulomatous pyelonephritis, a kidney inflammation due to bacterial infection, can rarely cause sinus formation. This case highlights sinuses developing post-nephrectomy, a rare occurrence.

Area of Science:

  • Nephrology
  • Pathology
  • Infectious Diseases

Background:

  • Xanthogranulomatous pyelonephritis (XGP) is a severe kidney inflammation caused by bacterial infection.
  • Histologic diagnosis typically occurs after kidney removal (nephrectomy).
  • Rarely, XGP can present with cutaneous fistulae and internal sinus tracts.

Purpose of the Study:

  • To report an unusual case of Xanthogranulomatous pyelonephritis.
  • To describe the late development of multiple internal and cutaneous sinuses.
  • To emphasize the potential for sinus formation two months after nephrectomy.

Main Methods:

  • Case report review.
  • Clinical and pathological data analysis.
  • Literature review on XGP and sinus formation.

Main Results:

  • A patient developed multiple internal and cutaneous sinuses.
  • Sinus formation was observed two months post-nephrectomy.
  • This presentation is a rare complication of Xanthogranulomatous pyelonephritis.

Conclusions:

  • Xanthogranulomatous pyelonephritis can lead to sinus formation, even after nephrectomy.
  • Late-onset sinus tracts are a rare but possible sequela.
  • This case underscores the importance of considering XGP complications beyond initial treatment.

Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...