Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hyperintense middle cerebral artery sign using MRI.

W W M Lam1, K S Wong, N M C So

  • 1Department of Diagnostic Radiology and Organ Imaging, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, People's Republic of China. wynnie@cuhk.edu.hk

Clinical Radiology
|July 2, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intracranial artery calcification to screen patients at high risk of recurrent stroke: abridged secondary publication.

Hong Kong medical journal = Xianggang yi xue za zhi·2020
Same author

Effect of a financial incentive on the acceptance of a smoking cessation programme with service charge: a cluster-controlled trial.

Hong Kong medical journal = Xianggang yi xue za zhi·2018
Same author

Translesional pressure gradient and leptomeningeal collateral status in symptomatic middle cerebral artery stenosis.

European journal of neurology·2017
Same author

Good collateral circulation predicts favorable outcomes in intravenous thrombolysis: a systematic review and meta-analysis.

European journal of neurology·2016
Same author

The prognosis of acute symptomatic seizures after ischaemic stroke.

Journal of neurology, neurosurgery, and psychiatry·2016
Same author

Unusual presentations of lymphocytic phlebitis of the digestive tract.

Pathology·2015

The hyperintense middle cerebral artery (MCA) sign on MRI indicates a worse prognosis in subacute stroke patients. This imaging marker correlates with higher National Institutes of Health Stroke Scale scores, suggesting its prognostic value.

Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Subacute ischemic stroke diagnosis and prognosis are critical for patient outcomes.
  • Identifying reliable imaging biomarkers for stroke severity is an ongoing area of research.

Purpose of the Study:

  • To evaluate the prognostic significance of the hyperintense middle cerebral artery (MCA) sign in subacute infarction.
  • To compare the utility of magnetic resonance imaging (MRI) versus computed tomography (CT) in detecting this sign.

Main Methods:

  • Twenty-five patients with suspected subacute ischemic stroke (6-48 hours post-symptom onset) underwent both MRI and CT.
  • Conventional T1 and T2-weighted MRI sequences were used to identify intraluminal thrombus (hyperintense MCA sign).
  • Results were correlated with the National Institutes of Health Stroke Scale (NIHSS) to assess stroke severity.

Related Experiment Videos

Main Results:

  • The hyperintense MCA sign was detected by MRI in 77.8% (T1-weighted) and 61.1% (T2-weighted) of patients.
  • CT identified the sign in only 38.9% of patients.
  • Patients with MRI-detected intraluminal thrombus exhibited significantly higher mean NIHSS scores (12.2 ± 8.0) compared to those without (4 ± 3.2, p=0.003).

Conclusions:

  • The presence of a hyperintense MCA sign on MRI is associated with increased stroke severity, as indicated by higher NIHSS scores.
  • This MRI finding holds prognostic value for subacute ischemic stroke.
  • MRI appears more sensitive than CT for detecting the hyperintense MCA sign in this context.