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Laser and proton radiation to reduce uveal melanoma-associated exudative retinal detachments
Devron H Char1, Riley Bove, Theodore L Phillips
1Tumori Foundation CPMC , San Francisco, California, USA. devron@tumori.org
Purpose:
To assess whether laser-induced hyperthermia with proton irradiation of choroidal melanoma may decrease exudative retinal detachments more rapidly.
Design:
Case control study.
Methods:
Patients treated with laser-induced hyperthermia and proton radiation; results were compared with similar patients treated with only protons.
Results:
All 11 patients treated with combined laser and proton therapy had resorption of subretinal fluid with a mean duration of retinal detachment of 193 days compared with 263 days in the group treated with only proton therapy (P <.04). At 1 year, visual acuity was similar.
Conclusions:
Combined laser radiation more rapidly dissipates exudative detachments than radiation alone.
