Related Experiment Video
Updated: Sep 23, 2026
In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Optical coherence tomographic and angiographic findings of a case with subretinal toxocara granuloma
Tomomi Higashide1, Nobuaki Akao, Etsuko Shirao
1Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan. eyetomo@kenroku-kanazawa-u.ac.jp
Purpose:
To study a case with a subretinal Toxocara granuloma.
Design:
Interventional case report.
Methods:
A patient with a exudative macular lesion, diagnosed as ocular toxocariasis, was examined with optical coherence tomography (OCT) and angiography before and after systemic corticosteroid and anthelminthic therapy.
Results:
In OCT images, the macular granuloma initially appeared as a highly reflective mass protruding above the retinal pigment epithelium and showed dye leakage by angiography. Posttherapy, the lesion was no longer exudative, was less elevated, and was covered by the retinal pigment epithelium. There was reticular hyperfluorescence surrounded by a hypofluorescent rim in the angiograms.
Conclusions:
Subretinal Toxocara granuloma may have a presentation similar to idiopathic choroidal neovascularization (CNV) and should be included in the differential diagnosis of the idiopathic CNV.
