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Mesalazine-associated benign intracranial hypertension in a patient with ulcerative colitis
Nicola Rosa1, Arcangelo Giamundo, Attilio Jura
1Eye Department, 2nd University of Naples, Naples, Italy. nocola.rosa@unina2.it
Purpose:
To report a case of benign intracranial hypertension related to mesalazine use.
Design:
Observational case report.
Methods:
A 23-year-old-woman with sudden visual loss, headache, and a history of ulcerative colitis treated with mesalazine underwent ophthalmologic examination, echography, magnetic resonance imaging, and lumbar puncture.
Results:
The examinations disclosed benign intracranial hypertension that resolved when mesalazine was discontinued and recurred when the drug was restarted.
Conclusions:
We recommend periodic ocular fundus examination for patients undergoing long-term therapy with mesalazine, especially if decreased vision, headaches, or neck stiffness are present, to avoid potentially severe complications of intracranial hypertension