Breast metastasis from non-small-cell lung carcinoma

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Primary Tumor and MEF Cell Isolation to Study Lung Metastasis
06:31

Primary Tumor and MEF Cell Isolation to Study Lung Metastasis

Published on: May 20, 2015

Kannan Ramar1, Hassan Pervez, Anil Potti

  • 1Department of Medicine, University of North Dakota School of Medicine, 1919 N Elm Street, Fargo, ND 58102, USA. kannanramar@yahoo.com

Medical Oncology (Northwood, London, England)
|July 2, 2003
PubMed

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Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...