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Updated: May 5, 2026

Experimental Metastasis and CTL Adoptive Transfer Immunotherapy Mouse Model
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Curing metastatic cancer: lessons from testicular germ-cell tumours
John R W Masters1, Beate Köberle
1The Prostate Cancer Research Centre, Institute of Urology, University College London, 3rd Floor, 67 Riding House Street, London W1W 7EJ, UK. j.masters@ucl.ac.uk
Abstract:
Most metastatic cancers are fatal. More than 80% of patients with metastatic testicular germ-cell tumours (TGCTs), however, can be cured using cisplatin-based combination chemotherapy. Why are TGCTs more sensitive to chemotherapeutics than most other tumour types? Answers to this question could lead to new treatments for metastatic cancers.
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