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E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro

J F Leeuwenberg1, E F Smeets, J J Neefjes

  • 1Department of Surgery, University of Limburg, Maastricht, The Netherlands.

Immunology
|December 1, 1992
PubMed
Summary

Researchers discovered that endothelial cells release soluble E-selectin and ICAM-1 adhesion molecules following cytokine activation. The release kinetics differ, with E-selectin peaking early and ICAM-1 later, potentially impacting inflammatory cell interactions.

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