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Related Experiment Videos

Sclerosing lobular hyperplasia: sonographic pathologic correlation.

Nariya Cho1, Ki Keun Oh, Kae Young Park

  • 1Department of Radiology, Yonsei University College of Medicine, Seoul, South Korea.

European Radiology
|July 2, 2003
PubMed
Summary

Sclerosing lobular hyperplasia (SLH) of the breast often presents as a circumscribed mass on ultrasound, sometimes with a characteristic echogenic septum. This septum on ultrasonography correlates with interlobular sclerosis on histopathology.

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Area of Science:

  • Radiology
  • Pathology
  • Breast Imaging

Background:

  • Sclerosing lobular hyperplasia (SLH) is a benign breast condition.
  • Accurate sonographic characterization of SLH is crucial for diagnosis and management.

Purpose of the Study:

  • To evaluate sonographic findings of sclerosing lobular hyperplasia (SLH).
  • To correlate sonographic features with histopathologic findings in SLH.

Main Methods:

  • Retrospective review of 9 ultrasonograms and 6 mammograms from patients with pathologically proven SLH.
  • Evaluation of mammographic and ultrasonographic features, including mass shape, margin, size, and presence of intratumoral echogenic septum.
  • Histopathologic correlation of imaging findings.

Main Results:

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  • Mammography showed lobular or oval masses with obscured margins in 4/6 cases; 2/6 showed dense breasts without masses.
  • Ultrasonography revealed lobular (5/9) or oval (4/9) shaped masses with circumscribed margins in all 9 cases.
  • An intratumoral echogenic septum, often peripherally arising, was present in 8/9 cases and correlated with interlobular sclerosis.

Conclusions:

  • Sonographic findings of SLH include circumscribed masses, often with a peripherally arising echogenic septum.
  • The echogenic septum observed on ultrasonography is likely due to interlobular sclerosis, aiding in the diagnosis of SLH.