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Adduct formation between oxanine and amine derivatives

T Nakano1, H Terato, K Asagoshi

  • 1Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, Higashi-Hiroshima 739-8526, Japan.

Nucleic Acids Research. Supplement (2001)
|July 3, 2003
PubMed
Summary

Nitric oxide (NO) creates Oxanine (Oxa), a guanine lesion. Oxa reacts with cellular amines like spermidine and lysine, revealing a new DNA damage pathway from NO.

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