Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Role for NMR in structural genomics.

Michael A Kennedy1, Gaetano T Montelione, Cheryl H Arrowsmith

  • 1Pacific Northwest National Laboratory, Environmental Molecular Sciences Laboratory, Richland, WA 99352, USA. ma_kennedy@pnl.gov

Journal of Structural and Functional Genomics
|July 3, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-throughput protein target mapping enables accelerated bioactivity discovery for ToxCast and PFAS compounds.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Large-scale discovery, analysis and design of protein energy landscapes.

Nature·2026
Same author

Comprehensive mass spectrometry screening-derived atlas of HDAC inhibitors reveals histone-specific acetylation changes.

Cell reports·2026
Same author

Structural basis of NSD2 degradation via targeted recruitment of SCF-FBXO22.

Nature communications·2026
Same author

Identification of E3 ligase substrates and PROTAC-induced ubiquitylation sites using proximity-based identification of ubiquitin sites (PrIUS).

Communications biology·2026
Same author

Dual-site phosphorylation of SLX4 stabilizes the SLX4-MUS81 interface to promote mitotic SMX assembly and genome protection.

Nucleic acids research·2026
Same journal

Protein sequence-similarity search acceleration using a heuristic algorithm with a sensitive matrix.

Journal of structural and functional genomics·2017
Same journal

Toward the next step in G protein-coupled receptor research: a knowledge-driven analysis for the next potential targets in drug discovery.

Journal of structural and functional genomics·2017
Same journal

Special issue: big data analyses in structural and functional genomics.

Journal of structural and functional genomics·2017
Same journal

Classification of ligand molecules in PDB with graph match-based structural superposition.

Journal of structural and functional genomics·2016
Same journal

VaProS: a database-integration approach for protein/genome information retrieval.

Journal of structural and functional genomics·2016
Same journal

NLDB: a database for 3D protein-ligand interactions in enzymatic reactions.

Journal of structural and functional genomics·2016
See all related articles

The 2nd EMSL Workshop on Structural Genomics explored the critical role of Nuclear Magnetic Resonance (NMR) in advancing structural and functional genomics. Key discussions focused on technical challenges and the potential need for a national NMR center to support this burgeoning scientific field.

Area of Science:

  • Structural biology
  • Genomics
  • Biophysics

Background:

  • The workshop convened experts to discuss the integration of Nuclear Magnetic Resonance (NMR) spectroscopy into structural and functional genomics.
  • Focus areas included the current capabilities and future potential of NMR in these rapidly evolving fields.

Framework:

  • The role of NMR in elucidating protein structures and functions within a genomic context.
  • Identification of technical hurdles and limitations hindering NMR's application in large-scale genomics projects.

Implementation:

  • Assessment of the feasibility and necessity for establishing a dedicated national NMR center in the United States.
  • Strategies for organizing the NMR research community to foster collaboration and resource sharing.

Related Experiment Videos

Implications:

  • The proceedings highlight the transformative potential of NMR for structural and functional genomics.
  • Recommendations address community organization and infrastructure development to accelerate progress in the field.