Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antiviral activity of Inonotus hispidus.

N A Awadh Ali1, R A A Mothana, A Lesnau

  • 1Institute of Pharmacy/Pharmaceutical Biology, Ernst-Moritz-Arndt University Greifswald, Friedrich-Ludwig-Jahn-Str 17, Greifswald 17487, Germany.

Fitoterapia
|July 3, 2003
PubMed
Summary

Two compounds, hispolon and hispidin, from the Inonotus hispidus fungus show antiviral activity. These compounds and fungal extracts are effective against influenza viruses A and B.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A coumarin with an unusual structure from <i>Cuphea ignea</i>, its cytotoxicity and antioxidant activities.

Die Pharmazie·2018
Same author

Four Cases of Yaws: With Remarks on the Importance of Recognising and Segregating Cases in India.

The Indian medical gazette·2017
Same author

Ethnobotany, chemical constituents and biological activities of the flowers of Hydnora abyssinica A.Br. (Hydnoraceae).

Die Pharmazie·2016
Same author

Beta vulgaris subspecies cicla var. flavescens (Swiss chard): flavonoids, hepatoprotective and hypolipidemic activities.

Die Pharmazie·2016
Same author

Phenolic profiling of an extract from Eugenia jambos L. (Alston)--the structure of three flavonoid glycosides--antioxidant and cytotoxic activities.

Die Pharmazie·2016
Same author

Phenolics from Caesalpinia ferrea Mart.: antioxidant, cytotoxic and hypolipidemic activity.

Die Pharmazie·2015

Area of Science:

  • Mycology
  • Virology
  • Natural Product Chemistry

Background:

  • The basidiomycete fungus Inonotus hispidus produces bioactive phenolic compounds.
  • Investigating natural products for antiviral properties is crucial for developing new therapeutics.

Purpose of the Study:

  • To evaluate the antiviral activity of hispolon and hispidin from Inonotus hispidus.
  • To assess the antiviral potential of fungal extracts against influenza viruses.

Main Methods:

  • Isolation of phenolic compounds (hispolon, hispidin) from Inonotus hispidus.
  • Preparation of extracts from fruit bodies and mycelial cultures.
  • Antiviral activity testing using the allantois on the shell-test system.

Main Results:

Related Experiment Videos

  • Ethanolic extracts demonstrated significant antiviral activity.
  • Isolated compounds, hispidin and hispolon, exhibited considerable antiviral effects.
  • Activity was observed against both influenza virus type A and type B.

Conclusions:

  • Hispolon and hispidin are potent antiviral agents against influenza viruses.
  • Inonotus hispidus is a potential source for novel antiviral compounds.
  • Further research into these compounds could lead to new anti-influenza treatments.