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Brain natriuretic peptide (BNP)-like immunoreactivity in the central nervous system of the crested newt
M F Franzoni1, M Canonaco, A Frova
1Dipartimento di Biologia Animale, Università di Torino, Italy.
European Journal of Histochemistry : EJH
|January 1, 1992
Abstract:
The distribution of brain natriuretic peptide (BNP)-like immunoreactivity (ir) was studied in the brain of a urodele amphibian, the crested newt Triturus carnifex Laur. BNP-like immunoreactive neurons were found mainly in the caudal hypothalamus (retro- and supra-chiasmatic areas) and in the preoptic area. A widespread innervation throughout the brainstem as far as the spinal cord was also observed. By double immunostaining (after section incubation with a-BNP and a-tyrosine hydroxylase-TH-antibodies), close topographical relationships between BNP-like and TH-like immunoreactive neurons within the hypothalamus were found.