[Delusion and Rose's disease]

A clinical case of a patient who was admitted to the psychiatric service due to persecutory type delusion manifestations, deterioration of general physical condition and dermatological disorders is presented. The psychiatric, family and personal background, on the one hand, and the cachectic condition of the patient, explained by the nutritional history, on the other, explain the psychitic expression of underlying vitamin-nutritional deficit. The clinical evolution presented after onset of treatment helps understand the etiological conditioning factors of the syndrome presented.