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Updated: Sep 23, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
[Comparison of craniofacial skeletal structures in adult high-angle and low-angle facial skeletal types]
Zhihe Zhao1, Danna Xiao, Hui Gao
1Department of Orthodontics, West China College of Stomatology, Sichuan University, Chengdu 610041, China.
Objective:
The purpose of this study was to compare the differences of craniofacial characteristics of adult high-angle and low-angle facial skeletal types.
Methods:
The subjects consisted of 37 yellow race adults (17 high-angle, 20 low-angle). Fifty-three items of cephlometic radiographs were analyzed.
Results:
The angle of N-S-Ar and N-S-Ba, the distance of Ptm-A, Co-Go, Po-NB, and S-Go, and the thickness of the mandibular symphysis in high-angle group were smaller than these in low-angle group. The angles of SN-OP, FH-OP, PP-OP, SN-MP, FH-MP, PP-MP, S-Ar-Go, mandibular angle(Ar-Go-Me), Y-angel and SUM, the distance of S-Co, N-Me, and ANS-Me in high-angle group were greater than these in low-angle group. The index of FHI, N-ANS/N-Me, and N-ANS/ANS-Me were smaller, and ANS-Me/N-Me larger in high-angle group. Although the means of Go-Po and FH-RP were smaller in high angle group, but no statistical difference were found.
Conclusion:
The craniofacial morphology of adult high-angle and low-angle facial skeletal types demonstrated significant differences, especially in lower facial form.
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