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Updated: Sep 23, 2026

Mouse Model of Surgically-induced Endometriosis by Auto-transplantation of Uterine Tissue
Published on: January 6, 2012
[Characteristics of estrous cycle and phagocytic activity of peritoneal macrophages in rats with experimental
Abstract:
Endometriosis is the growth of endometrial tissue outside the uterus. A rat model of endometriosis was used to evaluate the potential for surgical invasions. Experimental endometriosis in albino female rats was induced by autotransplantation of the uterine endometrium to the peritoneum near the ovary. In all the rats endometrial implants developed into endometriotic tissues. The reproductive function and phagocytic activity of peritoneal macrophages were assessed. Rats with endometriosis had longer diestrus and estrous cycle. Increased number of peritoneal macrophages and enhancement of their adhesion and phagocytic activity were registered.
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