Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ocular allergy: implications for the clinical immunologist.

C H Katelaris1

  • 1Institute of Immunology and Allergy Research, Westmead Hospital, Sydney, NSW, Australia. chk@allergyimmunol.com.au

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|July 4, 2003
PubMed
Summary

Ocular allergy, including allergic conjunctivitis, involves IgE-mediated responses and mast cell activation. More severe forms like vernal and atopic keratoconjunctivitis feature chronic inflammation and can threaten vision.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Urticaria and Angioedema: When East Meets West-and the Middle.

Allergy·2026
Same author

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria.

Allergy·2026
Same author

Developing a Standardised National Model of Care for Treatment of Peanut Allergy in Infants: The ADAPT Peanut Oral Immunotherapy Program.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2025
Same author

The global burden of chronic urticaria for the patient and society.

The British journal of dermatology·2020
Same author

The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria.

Allergy·2018
Same author

Outdoor pollen is a trigger of child and adolescent asthma emergency department presentations: A systematic review and meta-analysis.

Allergy·2018

Area of Science:

  • Ophthalmology
  • Allergy and Immunology
  • Pathogenesis of Ocular Diseases

Background:

  • Ocular allergic diseases are common, affecting the external eye.
  • Most forms involve IgE-mediated responses and mast cell activation, similar to other atopic conditions.
  • Severe forms like vernal and atopic keratoconjunctivitis involve chronic inflammation and pose a risk to vision.

Purpose of the Study:

  • To overview ocular allergic conditions.
  • To summarize current knowledge on immunopathogenetic mechanisms driving these diseases.

Main Methods:

  • Literature review of English-language articles.
  • MEDLINE search from 1995.
  • Focus on recent advances in understanding pathogenesis.

Related Experiment Videos

Main Results:

  • Ocular allergy pathogenesis involves IgE-mediated responses and mast cell mediators like histamine.
  • Seasonal and perennial allergic conjunctivitis are typically self-limited.
  • Vernal and atopic keratoconjunctivitis exhibit complex, chronic immune inflammation with T cell infiltration.

Conclusions:

  • Advances in understanding ocular allergy pathogenesis improve treatment strategies.
  • New treatment modalities are being developed.
  • Improved symptom control for patients is achievable.