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Malignant otitis externa due to Aspergillus niger.

Cristina Bellini1, Pietro Antonini, Stefano Ermanni

  • 1Division of Infectious Diseases, Hospital of Lugano, Switzerland.

Scandinavian Journal of Infectious Diseases
|July 4, 2003
PubMed
Summary

A diabetic patient recovered from malignant otitis externa caused by Aspergillus niger with antifungal therapy. This case and 13 others highlight Aspergillus species as a cause of this serious ear infection.

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Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Mycology

Background:

  • Malignant otitis externa (MOE) is a severe infection of the external auditory canal, often seen in elderly, diabetic patients.
  • Aspergillus species are known pathogens, but their role in MOE requires further characterization.

Observation:

  • A 73-year-old diabetic male presented with malignant otitis externa.
  • The causative agent was identified as Aspergillus niger.

Findings:

  • Successful treatment involved intravenous amphotericin B for 3 weeks, followed by 3 months of oral itraconazole.
  • Analysis of 13 reported cases of Aspergillus-induced MOE reveals treatment outcomes and clinical characteristics.

Implications:

  • This case underscores the importance of considering Aspergillus in refractory or severe cases of otitis externa, particularly in immunocompromised individuals.

Related Experiment Videos

  • Effective antifungal strategies, including amphotericin B and azoles, are crucial for managing Aspergillus-related MOE.