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Radiofrequency tissue ablation: an early Indian experience
Subodh Varshney1, Sandesh Sharma, Viniyendra Pamecha
1Department of Surgical Gastroenterology and Clinical Nutrition, Bhopal Memorial Hospital and Research Center, Bhopal. subodhvarshney@rediffmail.com
Summary
Radiofrequency (RF) tumor ablation is a safe and effective treatment for malignant lesions in Indian patients. This minimally invasive technique shows promising results, particularly for smaller tumors, with low complication rates.
Area of Science:
- Oncology
- Interventional Radiology
- Surgical Oncology
Background:
- Radiofrequency (RF) tissue ablation is an established percutaneous local tissue ablation therapy in Western countries.
- This study evaluates the safety and efficacy of RF tissue ablation for malignant lesions in an Indian patient cohort.
Purpose of the Study:
- To assess the effectiveness of RF tumor ablation in treating various malignant lesions.
- To evaluate the safety profile and complication rates associated with RF tumor ablation.
Main Methods:
- RF tumor ablation was performed using an RF generator delivering 35-50 RF watts.
- Needle placement was image-guided (n=22) or during open surgery (n=1).
- The procedure was applied to 73 lesions in 23 patients over 21 months, including liver metastases and pancreatic cancer.
Main Results:
- Complete tumor necrosis was achieved in all lesions <3 cm and 39% of lesions 3-4 cm.
- Local recurrence was observed in only 6.2% of lesions with complete necrosis.
- The procedure demonstrated a favorable safety profile with no mortality or major morbidity, and low rates of minor complications like ascites and pleural effusion.
Conclusions:
- RF tumor ablation is a safe and effective local tissue ablative method for malignant lesions in Indian patients.
- The technique shows significant efficacy, especially for smaller lesions, and is well-tolerated.