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Laryngeal tuberculosis: an often forgotten diagnosis
Paolo Boscolo Rizzo1, Maria Cristina Da Mosto, Maurizio Clari
1ENT Department, University of Padua, Treviso Regional Hospital, Treviso, Italy.
Summary
Laryngeal tuberculosis, though rare, can present with laryngeal symptoms and requires diagnosis via biopsy and sputum examination. Standard antituberculosis therapy leads to full recovery in affected patients.
Area of Science:
- Pulmonology
- Infectious Diseases
- Otolaryngology
Background:
- Laryngeal tuberculosis (LTB) is an uncommon manifestation of Mycobacterium tuberculosis infection.
- Historically, LTB incidence declined significantly post-1950s.
- Resurgence of pulmonary tuberculosis has been associated with increased LTB cases.
Observation:
- This study presents three cases of LTB in HIV-negative individuals with coexisting lung involvement.
- Patients predominantly exhibited laryngeal symptoms, potentially masking the underlying infection.
- Diagnosis was confirmed through laryngeal biopsy and sputum analysis.
Findings:
- All three patients received standard antituberculosis therapy.
- Complete recovery was observed in all cases following treatment.
- Early and accurate diagnosis is crucial for effective management.
Implications:
- LTB, despite its rarity, remains a diagnostic challenge, often leading to misdiagnosis.
- Increased vigilance for LTB is warranted in patients with pulmonary tuberculosis.
- Prompt diagnosis and treatment of LTB ensure favorable patient outcomes.