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Murine Model of CD40-activation of B cells
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Murine Model of CD40-activation of B cells

Published on: March 5, 2010

Anti-proliferative effects induced by anti-CD4 human/murine chimeric antibody and murine anti-CD4 monoclonal antibody

G Shen1, H Zhu, X Wang

  • 1Department of Immunology, Tongji Medical University, Wuhan 430030.

Journal of Tongji Medical University = Tong Ji Yi Ke Da Xue Xue Bao
|July 5, 2003
PubMed

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Hybridoma Technology01:31

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Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...