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Updated: Sep 23, 2026

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Published on: August 16, 2018
A convenient two step protocol for the synthesis of cyclopentenones and indanones, including an asymmetric variant
Daniel J Kerr1, Christiane Metje, Bernard L Flynn
1Department of Chemistry, The Faculties, Australian National University, Canberra ACT, 0200, Australia.
Abstract:
A one-pot palladium mediated hydrostannylation/cross-coupling protocol is used to give direct access to cross-conjugated dienones that can be utilized in Nazarov cyclizations to afford highly substituted cyclopentenones and indanones, including an asymmetric variant.
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